Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ILUVIEN | Alimera Sciences | N-201923 RX | 2014-09-26 | 1 products, RLD, RS |
YUTIQ | Alimera Sciences | N-210331 RX | 2018-10-12 | 1 products, RLD, RS |
RETISERT | Bausch Health Companies | N-021737 RX | 2005-04-08 | 1 products, RLD, RS |
DERMA-SMOOTHE/FS | Hill Dermaceuticals | N-019452 RX | 1988-02-03 | 2 products, RLD, RS |
DERMOTIC | Hill Dermaceuticals | N-019452 RX | 2005-11-09 | 1 products, RLD, RS |
SYNALAR | Medimetriks Pharmaceuticals | N-012787 RX | 1982-01-01 | 3 products, RLD, RS |
SYNALAR | Medimetriks Pharmaceuticals | N-013960 RX | 1982-01-01 | 1 products, RLD, RS |
SYNALAR | Medimetriks Pharmaceuticals | N-015296 RX | 1982-01-01 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
OTOVEL | Laboratorios Salvat | N-208251 RX | 2016-04-29 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
ciprofloxacin and fluocinolone acetonide | NDA authorized generic | 2024-10-09 |
derma-smoothe/fs | New Drug Application | 2024-09-12 |
dermotic | New Drug Application | 2024-05-17 |
flac otic oil | ANDA | 2024-11-19 |
fluocinol pak | unapproved drug other | 2023-01-11 |
fluocinolone acetonide | ANDA | 2024-12-19 |
fluocinolone acetonide 0.01% | NDA authorized generic | 2024-01-30 |
fluocinolone acetonide 0.01% / minoxidil 5% / tretinoin 0.025% | unapproved drug other | 2019-05-08 |
fluocinolone acetonide 0.01% / minoxidil 7% / progesterone 0.1% | unapproved drug other | 2019-05-08 |
fluocinolone acetonide 0.01% / niacinamide 4% | unapproved drug other | 2019-05-13 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Uveitis | D014605 | HP_0000554 | H20.9 | 2 | 3 | 8 | 5 | 5 | 20 |
Macular edema | D008269 | — | — | 1 | 5 | 5 | 6 | 4 | 18 |
Edema | D004487 | HP_0000969 | R60.9 | 1 | 5 | 5 | 5 | 2 | 15 |
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 2 | 3 | 2 | 1 | 8 |
Dermatitis | D003872 | HP_0011123 | L30.9 | — | 2 | 3 | 2 | 1 | 8 |
Posterior uveitis | D015866 | EFO_1001119 | — | 1 | 1 | 4 | 1 | 2 | 8 |
Eczema | D004485 | HP_0000964 | L30.9 | — | 2 | 2 | 2 | 1 | 7 |
Melanosis | D008548 | HP_0001480 | L81.1 | — | 1 | — | 4 | 1 | 6 |
Alopecia areata | D000506 | EFO_0004192 | L63 | — | — | — | 1 | — | 1 |
Alopecia | D000505 | HP_0002293 | L64 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | 1 | — | — | 5 |
Intermediate uveitis | D015867 | EFO_1000986 | — | — | — | 3 | — | 1 | 4 |
Pars planitis | D015868 | EFO_1001088 | H30.2 | — | — | 3 | — | 1 | 4 |
Retinal diseases | D012164 | HP_0000479 | H35.9 | — | 1 | 2 | — | — | 2 |
Radiation injuries | D011832 | — | — | — | 1 | 2 | — | — | 2 |
Panuveitis | D015864 | EFO_1001082 | H44.11 | 1 | — | 1 | — | — | 2 |
Inflammation | D007249 | MP_0001845 | — | — | — | 1 | — | 1 | 2 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | 1 | 1 | — | — | 1 |
Infections | D007239 | EFO_0000544 | — | — | — | 1 | — | — | 1 |
Communicable diseases | D003141 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | 3 | — | — | — | 4 |
Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | 1 | 1 | — | — | 1 | 3 |
Lentigo | D007911 | — | L81.4 | — | 1 | — | — | 1 | 2 |
Neoplasms | D009369 | — | C80 | 1 | 1 | — | — | — | 2 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 1 | — | — | — | 2 |
Hand-foot syndrome | D060831 | EFO_1001893 | — | — | 1 | — | — | — | 1 |
Exanthema | D005076 | HP_0000988 | — | — | 1 | — | — | — | 1 |
Geographic atrophy | D057092 | — | — | — | 1 | — | — | — | 1 |
Atrophy | D001284 | — | — | — | 1 | — | — | — | 1 |
Lymphatic metastasis | D008207 | EFO_1001364 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Psoriasis | D011565 | EFO_0000676 | L40 | 2 | — | — | — | 1 | 3 |
Glaucoma | D005901 | EFO_0000516 | H40 | 2 | — | — | — | — | 2 |
Choroidal neovascularization | D020256 | — | — | 1 | — | — | — | — | 1 |
Pathologic neovascularization | D009389 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Oral lichen planus | D017676 | — | — | — | — | — | — | 2 | 2 |
Lichen planus | D008010 | — | L43 | — | — | — | — | 2 | 2 |
Mycoses | D009181 | — | B35-B49 | — | — | — | — | 1 | 1 |
Lymphoma | D008223 | — | C85.9 | — | — | — | — | 1 | 1 |
T-cell lymphoma | D016399 | — | — | — | — | — | — | 1 | 1 |
T-cell lymphoma peripheral | D016411 | — | — | — | — | — | — | 1 | 1 |
Mycosis fungoides | D009182 | — | C84.0 | — | — | — | — | 1 | 1 |
T-cell lymphoma cutaneous | D016410 | — | — | — | — | — | — | 1 | 1 |
Cutaneous lupus erythematosus | D008178 | EFO_0003834 | L93.1 | — | — | — | — | 1 | 1 |
Candidiasis | D002177 | — | B37 | — | — | — | — | 1 | 1 |
Drug common name | Fluocinolone acetonide |
INN | fluocinolone acetonide |
Description | Fluocinolone acetonide is a fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatment of various skin disorders. It has a role as an anti-inflammatory drug and an antipruritic drug. It is an 11beta-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a cyclic ketal, a glucocorticoid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid, an organic heteropentacyclic compound and a primary alpha-hydroxy ketone. |
Classification | Small molecule |
Drug class | steroids (not prednisolone derivatives); topical steroids (acetal derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 |
PDB | — |
CAS-ID | 67-73-2 |
RxCUI | — |
ChEMBL ID | CHEMBL989 |
ChEBI ID | 31623 |
PubChem CID | 6215 |
DrugBank | DB00591 |
UNII ID | 0CD5FD6S2M (ChemIDplus, GSRS) |